Method of preparing dl-w-carboxy-1-hexyl-5-/3'-acetoxy-1'-octene/-(e)-yl/-2-pyrrolidinone
专利摘要:
Prostaglandin derivatives corresponding to the general formula: <IMAGE> wherein R1 represents hydrogen, methyl or ethyl, R2, R3 and R4, which are the same or different, each represent hydrogen or methyl and R is selected from the groups consisting of: <IMAGE> <IMAGE> in which R5 represents hydrogen, methyl or ethyl, R6 represents methyl, ethyl or acetyl and R7 and R8, when they are different, each represent hydrogen or a branched- or straight-chain alkyl group having from 1 to 7 carbon atoms or R7 and R8, when they are identical, each represent hydrogen or a straight-chain alkyl group having from 1 to 3 carbon atoms with the provisos that: 公开号:SU715019A3 申请号:SU782595450 申请日:1978-03-30 公开日:1980-02-05 发明作者:Нантавонг Сули;Пижеруа Шарль;Эймар Пьер;Симиан Жак 申请人:Лябаз С.А. (Фирма); IPC主号:
专利说明:
Nuclear Magnetic Resonance Spectrum (CDCla), b: 2.0 (CH3SO), 5 (), 7.4 (COOH).
权利要求:
Claims (1) [1] 1. Carrer P. The course of organic chemistry. M., 1960, p. 262.
类似技术:
公开号 | 公开日 | 专利标题 SU715019A3|1980-02-05|Method of preparing dl-w-carboxy-1-hexyl-5-/3'-acetoxy-1'-octene/-|-yl/-2-pyrrolidinone FR2409992A1|1979-06-22|NEW 2-HALOMETHYL-5-VINYL-1,3,4-OXADIAZOLES IE40913L|1975-10-09|Amides IE811832L|1982-02-12|Indoles. ES8104391A1|1981-04-16|Low-foaming alkoxy-bis|-silane surfactants IE45590L|1978-03-17|Anilines. CA2070663A1|1992-04-13|Sulfonating agent and process ES467496A1|1979-08-01|Imidazole derivatives JPS5637244B2|1981-08-29| ES448549A1|1977-07-01|Process for preparing azomethines JPS52116495A|1977-09-29|Novel naphthyridine derivatives ES459186A1|1978-11-01|Polyprenyl carboxylic acid compound ES471267A1|1979-10-01|Lower alkyl 2-tri-|alkylsilylacetylene-N-carbethoxyglycinates and process for using same ES8200648A2|1981-12-01|Ionic polyiodo benzene derivatives useful as X-ray contrast media ES8100796A1|1980-11-01|N-|acetamide derivatives, and their production and use ES451209A1|1977-12-16|Antispasmodic substituted sulphoximides JPS5432427A|1979-03-09|Novel diphenyl ether compounds and herbicides ES453997A1|1977-11-16|Secondary etheramine acetates and their use as lubricating agents for synthetic fibers ES441437A1|1977-07-01|3-Methoxy crotonanilides as herbicides ES8101609A1|1980-12-16|A 7 alpha -methoxycephalosporin derivative and process for producing the same ES467387A1|1978-11-16|Novel substituted methylene bridged aluminum oligomers JPS5416466A|1979-02-07|Novel 3-hydroxypyrrolldine-3-carboxylic derivative GB2013497A|1979-08-15|Herbicides ES8403102A1|1984-03-01|Fluorophenoxybenzyl esters, their preparation and use as pesticides. JPH03134192A|1991-06-07|Production of low-melting composition
同族专利:
公开号 | 公开日 NO149428B|1984-01-09| DE2714129A1|1977-10-13| BE852941A|1977-09-28| IL49325A|1979-11-30| PL107544B1|1980-02-29| CH628032A5|1982-02-15| CA1074804A|1980-04-01| NO149428C|1984-04-18| HU178040B|1982-02-28| NO771134L|1977-10-03| ES457385A1|1978-02-01| JPS52142060A|1977-11-26| DD130352A5|1978-03-22| IL49325D0|1976-05-31| PL107643B1|1980-02-29| CH624101A5|1981-07-15| PL108289B1|1980-03-31| SE7703698L|1977-10-01| NL7703503A|1977-10-04| SE417603B|1981-03-30| SU837321A3|1981-06-07| FR2346332B1|1980-05-09| FR2346332A1|1977-10-28| IT1075373B|1985-04-22| GB1574246A|1980-09-03| SU676162A3|1979-07-25| US4115401A|1978-09-19| PL197005A1|1978-10-09|
引用文献:
公开号 | 申请日 | 公开日 | 申请人 | 专利标题 US3975399A|1974-08-06|1976-08-17|E. I. Du Pont De Nemours And Company|1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones|DK290079A|1978-07-11|1980-01-12|Glaxo Group Ltd|PROCEDURE FOR THE PREPARATION OF PROSTANOID COMPOUNDS| US4320136A|1980-08-11|1982-03-16|E. I. Du Pont De Nemours And Company|8-Aza-16,16-difluoroprostanoids| US4456613A|1982-12-27|1984-06-26|E. I. Du Pont De Nemours And Company|6-Keto- and 6-hydroxy-8-azaprostanoids and anti-ulcer use thereof| US4530933A|1982-12-27|1985-07-23|E. I. Du Pont De Nemours And Company|8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulcer agents| MXPA02006322A|1999-12-22|2002-12-13|Pfizer Prod Inc|Ep4 receptor selective agonists in the treatment of osteoporosis.| PL362030A1|2000-11-27|2004-10-18|Pfizer Products Inc.|Ep4 receptor selective agonists in the treatment of osteoporosis| CA2451393C|2001-07-16|2011-01-04|F. Hoffmann-La Roche Ag|2 pyrrolidone derivatives as prostanoid agonists| JP2004521954A|2001-07-16|2004-07-22|エフ.ホフマン−ラ ロシュ アーゲー|Prostaglandin analogs as EP4 receptor agonists| DE60239343D1|2001-07-23|2011-04-14|Ono Pharmaceutical Co|MEDICINE FOR THE TREATMENT OF DISEASES COMING WITH BONE SCUM, WITH EP4 AGONIST AS AN ACTIVE AGENT| CA2477715A1|2002-03-05|2003-09-12|Ono Pharmaceutical Co., Ltd.|8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient| AU2003209571A1|2002-03-18|2003-09-29|Pfizer Products Inc.|Use of selective ep4 receptor agonists for the treatment of liver failure, loss of patency of the ductus arteriosus, glaucoma or ocular hypertension| BRPI0406717A|2003-01-10|2005-12-20|Hoffmann La Roche|Compound, pharmaceutical composition comprising the same, method of treating a disease in a mammal, use of the compound and process for its production| US20080058375A1|2004-01-08|2008-03-06|Elworthy Todd R|2-Piperidone derivatives as prostaglandin antagonists| US7179820B2|2003-06-06|2007-02-20|Allergan, Inc.|Piperidinyl prostaglandin E analogs|
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